Malignant neoplasms following bone marrow transplantation
نویسندگان
چکیده
منابع مشابه
Malignant neoplasms following bone marrow transplantation.
We undertook an analysis of 2,150 recipients of bone marrow transplant (BMT) at the University of Minnesota to determine the incidence of post-BMT malignant neoplasms (MNs). Fifty-one patients developed 53 MNs, compared with 4.3 expected from general population rates (standardized incidence ratio [SIR], 11.6, 95% confidence interval [CI], 8.2-14.5). These included 22 occurrences of B-cell lymph...
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OBJECTIVE Malignancies have long been recognized as a complication of long lasting immunosuppressive therapy. We reviewed our experience to investigate the incidence and the spectrum of non cutaneous de novo malignant neoplasms. METHODS Between March 1987 and March 1996, 296 patients underwent 303 cardiac transplantation in our service. The population at risk consists of all patients survivin...
متن کاملMalignant osteopetrosis: hypercalcaemia after bone marrow transplantation.
A 3 year old girl presented with malignant osteopetrosis, which was treated by allogeneic bone marrow transplantation. Successful engraftment was complicated by prolonged hypercalcaemia, which was controlled by a combination of a bisphosphonate, phosphate infusions, vigorous resalination, and salmon calcitonin. She was alive and well 16 months after the transplant.
متن کاملBone marrow transplantation for non-malignant disease.
Bone marrow transplantation (BMT) has emerged as a major therapeutic option for a number of nonmalignant disorders affecting the bone marrow and leading to clinical manifestations most likely affecting distant organs. Disorders such as autoimmune diseases, metabolic disorders, hemoglobinopathies, immunodeficiencies, and others have been the target of high-dose therapy and autologous or allogene...
متن کاملMalignant osteopetrosis: hypercalcaemia after bone marrow transplantation
Discussion In this case engraftment was followed by a rapid rise in the calcium concentration, and hypercalcaemia recurred on a number of occasions. A management plan to control the serum calcium concentration during these acute phases and to maintain long term normocalcaemia evolved with experience. In the acute phase the hypercalcaemia seemed to be controlled primarily by a combination of reh...
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ژورنال
عنوان ژورنال: Blood
سال: 1996
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v87.9.3633.bloodjournal8793633